甄淑君（Shu Jun Zhen）

教授博导国家优秀青年科学基金获得者

个人简介

于2006年在西南大学获得环境科学学士学位，2011年在西南大学获得分析化学博士学位，2011年留校任教，2013年12月至2014年12月在美国德克萨斯大学奥斯汀分校访学，2014年晋升副教授，2021年晋升教授。到目前为止，以第一作者或通讯作者身份在Angew. Chem. Int. Ed.、Adv. Funct. Mater.、Anal. Chem.、Small等期刊上发表学术论文50多篇，授权专利3项。获2012年重庆市优秀博士学位论文、 2016年西南大学第十一届教师课堂教学比赛二等奖、西南大学2018年优秀本科生班主任、2021年第七届中国国际“互联网+”大学生创新创业大赛重庆赛区选拔赛高教主赛道优秀创新创业导师。近年来，获得国家优秀青年科学基金、国家自然科学基金面上项目、青年基金、国家重点研发计划子课题、重庆市基础与前沿研究重点项目、一般项目、重庆市自然科学基金面上项目、教育部新教师基金、中央高校基本科研业务费（人才团队项目、重点项目、一般项目）等科研基金的资助。

联系方式

邮箱：zsj@swu.edu.cn

研究方向

共振能量转移光谱分析

代表性论文

1. Li, C.; Lv, W.; Yang, F.; Li, C.; Huang, C.*;Zhen, S.*Logic Control of Directional Long-Range Resonance Energy Transfer On 2D DNA Nanosheet.Small2023, 2301811.

2. Lv, W. Y.; Li, L. L.; Guan, C. Y.; Li, C. M.; Huang, C. Z.*;Zhen, S. J.*Rational Design of Cascade DNA System for Signal Amplification.Anal. Chem.2023,95, 7603−7610.

3. Xie, T. J.; Xie, J. L.; Luo, Y. J.; Mao, K.; Huang, C. Z.; Li, Y. F.;Zhen, S. J.*CRISPR-Cas12a Coupled with DNA Nanosheet-Amplified Fluorescence Anisotropy for Sensitive Detection of Biomolecules.Anal. Chem.2023,95, 7237−7243.

4. Cao, L. P.; Li, C. M.;Zhen, S. J.*; Huang, C. Z.* A General Signal Amplifier of Self-Assembled DNA Micelles for Sensitive Quantification of Biomarkers.Anal. Chem.2023,95, 1794−1800.

5. Lv, W. Y.; Li, C. H.; Yang, F. F.; Li, Y. F.;Zhen, S. J.*; Huang, C. Z.* Sensitive Logic Nanodevices with Strong Response for Weak Inputs.Angew. Chem. Int. Ed.2022, e202115561.

6. Cao, L. P.; Wang, Y.; Bai, Y.; Jiang, Y. J.; Li, C. M.; Li, Y. F.; Huang, C. Z.*;Zhen, S. J.*Metal–organic gel coupled entropy-driven circuit for fluorescence detection of miR-155.J. Mater. Chem. C2022,10, 18258–18263.

7. Tian, L. L.; Li, C. H.; Ye, Q. C.; Li, Y. F.; Huang, C. Z.; Zhan, L.; Wang, D. M.;Zhen, S. J.* A centrifugal microfluidic chip for point-of-care testing of staphylococcal enterotoxin B in complex matrices.Nanoscale2022,14, 1380–1385.

8. Yang F. F.; Li, C. H.; Lv, W. Y.;Zhen, S. J.*; Huang, C. Z.* Deoxyribonucleic Acid Photonic Wires with Three Primary Color Emissions for Information Encryption.Adv. Funct. Mater.2021,31, 2100322.

9. Li, C. H.; Lv, W. Y.; Yan, Y.; Yang F. F.;Zhen, S. J.*; Huang, C. Z.* Nucleolin-Targeted DNA Nanotube for Precise Cancer Therapy through For̈ster Resonance Energy Transfer-Indicated Telomerase Responsiveness.Anal. Chem.2021,93, 3526−3534.

10. Lv, W. Y.; Li, C. H.; Li, Y. F.;Zhen, S. J.*; Huang, C. Z.* Hierarchical Hybridization Chain Reaction for Amplified Signal Output and Cascade DNA Logic Circuits.Anal. Chem.2021,93, 3411−3417.

11. Ye, Q. C.; Men, C.; Li, Y. F.; Liu, J. J.; Huang, C. Z.;Zhen, S. J.* Catalytic hairpin assembly mediated liposome encoded magnetic beads for signal amplification of peroxide test strip based point-of-care testing of ricin.Chem. Commun.2020,56, 14091−14094.

12. Li, C. H.; Li, R. S.; Li, C. M.; Huang, C. Z.*,Zhen, S. J.* Precise ricin A-chain delivery by Golgi-targeting carbon dots.Chem. Commun.2019,55, 6437−6440.

13.Zhen, S. J.*; Xiao, X.; Li, C. H.; Huang, C. Z. An Enzyme-Free DNA Circuit-Assisted Graphene Oxide Enhanced Fluorescence Anisotropy Assay for MicroRNA Detection with Improved Sensitivity and Selectivity.Anal. Chem.2017,89, 8766−8771.

14. Li, C. H.; Xiao, X.; Tao, J.; Wang, D. M.; Huang, C. Z.;Zhen, S. J.* A graphene oxide-based strand displacement amplification platform for ricin detection using aptamer as recognition element.Biosens. Bioelectron.2017,91, 149–154.

15. Du, Y.;Zhen, S. J.(共同一作); Li, B.; Byrom, M.; Jiang, Y. S.; Ellington, A. D. Engineering signaling aptamers that rely on kinetic rather than equilibrium competition.Anal. Chem.2016,88, 2250−2257.

16. Xiao, X.; Tao, J.; Zhang, H. Z.; Huang, C. Z.;Zhen, S. J.* Exonuclease III-assisted graphene oxide amplified fluorescence anisotropy strategy for ricin detection.Biosens. Bioelectron.2016,85, 822–827.

17. Xiao, X.; Li Y. F.; Huang, C. Z.*;Zhen, S. J.* A novel graphene oxide amplified fluorescence anisotropy assay with improved accuracy and sensitivity.Chem. Commun.2015,51, 16080−16083.

18. Yu, Y.; Liu, Y.;Zhen, S. J.*; Huang, C. Z.* A graphene oxide enhanced fluorescence anisotropy strategy for DNAzyme-based assay of metal ions.Chem. Commun.2013,49, 1942−1944.

19.Zhen, S. J.; Guo, F. L.; Chen, L. Q.; Li, Y. F.; Zhang, Q.; Huang, C. Z.* Visual detection of cobalt(II) ion in vitro and tissue with a new type of leaf-like molecular microcrystal.Chem. Commun.2011,47, 2562−2564.

20.Zhen, S. J.; Chen, L. Q.; Xiao, S. J.; Li, Y. F.; Hu, P. P.; Zhan, L.; Peng, L.; Song, E. Q.; Huang, C. Z.* Carbon nanotubes as a low background signal platform for a molecular aptamer beacon on the basis of long-range resonance energy transfer.Anal. Chem.2010,82, 8432−8437.