何延红
教授、博士生导师
个人简介
1984.09 - 1988.06，云南大学，分析化学，学士学位
1988.06 - 1996.08，云南省热带作物科学研究所，助理研究员
1996.09 - 1999.06，中山大学，有机化学，硕士学位，导师：曾陇梅教授
1999.06 - 2001.02，中山大学化学与化学工程学院，讲师
2001.03 - 2004.11，瑞典隆德(Lund)大学，有机化学，博士学位，导师：Olov Sterner 教授
2005.12 - 2016.06，西南大学化学化工学院，特聘教授，副教授
2016.07 - 至今, 西南大学化学化工学院，教授
先后主持国家自然科学基金面上项目2项、国家自然科学基金应急管理项目1项、省部级项目多项。迄今, 在《Angew. Chem. Int. Ed.》、《Org. Lett.》、《Green Chem.》、《ACS Sustainable Chem. Eng.》、《Org. Chem. Front.》、《Chem. Commun.》、《J. Org. Chem.》等国际学术刊物上发表SCI收录论文140余篇；获授权发明专利24项；科研成果获重庆市2015年度自然科学二等奖（排名第二）、2020年重庆市化学化工学会基础研究成果奖一等奖（排名第一）。研究工作两次被美国《化学与工程新闻》（Chemical & Engineering News, C&EN）报道。
联系方式
E-mail：heyh@swu.edu.cn
研究方向
酶催化的有机合成、光氧化还原催化和电化学促进的自由基反应研究。
代表性论文、专著和专利（不超过20项）
[1] Chao-Jiu Long, Huan Cao, Ben-Kun Zhao, Yu-Fang Tan, Yan-Hong He*, Chu-Sheng Huang*, Zhi Guan*. Merging the non-natural catalytic activity of lipase and electrosynthesis: asymmetric oxidative cross-coupling of secondary amines with ketones. Angew. Chem. Int. Ed., 2022, 61(30), e202203666.
[2] Xuan Ding, Chun-Lin Dong, Zhi Guan*, Yan-Hong He*. Concurrent asymmetric reactions combining photocatalysis and enzymatic catalysis: direct enantioselective synthesis of 2,2-disubstituted indol-3-ones from 2-arylindoles. Angew. Chem. Int. Ed., 2019, 58(1), 118-124.
[3] Ming-Lin Yang, Zhi Guan*, Yan-Hong He*. Photoredox catalyzed radical–radical cross-coupling of α-ketoesters with ethers: access to sterically hindered α-hydroxy esters. Org. Lett., 2023, 25(48), 8596-8600.
[4] Yu-Hao Yang‡, Yu-Fang Tan‡, Ya-Nan Zhao, Yan-Hong He*, Zhi Guan*. Electrosynthesis of 5-aminocoumaran derivatives from olefins and aminophenols. Org. Lett., 2023, 25(46), 8205-8209.
[5] Wei-Mei Zeng, Yan-Hong He*, Zhi Guan*. Direct reductive arylation of imines with electron-deficient (Hetero) arenes via electrosynthesis to access benzylic amines. Org. Lett., 2022, 24(39), 7178-7182.
[6] Hao-Luo Jiang, Yu-Hao Yang, Yan-Hong He*, Zhi Guan*. Visible-light-catalyzed radical-radical cross-coupling reaction of benzyl trifluoroborates and carbonyl compounds to sterically hindered alcohols. Org. Lett., 2022, 24(23), 4258-4263.
[7] Li Tang, Zhi-Lv Wang, Hai-Lan Wan, Yan-Hong He*, Zhi Guan*. Visible-light-induced Beckmann rearrangement by organic photoredox catalysis. Org. Lett., 2020, 22(15), 6182-6186.
[8] Chun-Lin Dong, Xuan Ding, Lan-Qian Huang, Yan-Hong He*, Zhi Guan*. Merging visible light photocatalysis and L-/D-proline catalysis: direct asymmetric oxidative dearomatization of 2-arylindoles to access C2-quaternary indolin-3-ones. Org. Lett., 2020, 22(3), 1076-1080.
[9] Li Tang, Xing-Meng Li, Jack H. Matuska, Yan-Hong He,* and Zhi Guan*. Intramolecular transamidation of secondary amides via visible light induced tandem reaction. Org. Lett., 2018, 20(18), 5618-5621.
[10] Yu-Fang Tan, Dan Yang, Yu-Hao Yang, Jin-Feng Lv, Lan-Xi Zong, Zhi Guan*, Yan-Hong He*. Electricity-driven 1,4-alkoxydimerization of alkenes via radical-polar crossover. Green Chem., 2023, 25(22), 9388-9393.
[11] Yu-Fang Tan, Dan Yang, Ya-Nan Zhao, Jin-Feng Lv, Zhi Guan*, Yan-Hong He*. Electrochemical radical-polar crossover diesterification of alkenes with carboxylic acids. Green Chem., 2023, 25(4), 1540-1545.
[12] Wei-Mei Zeng‡, Zhi-Lv Wang‡, Yan-Hong He*, Zhi Guan*. Electrochemical radical-radical cross-coupling: direct access to β-amino nitriles from unactivated imines and alkyl nitriles. Green Chem., 2022, 24(12), 4928-4934.
[13] Yu-Fang Tan‡, Chao-Jiu Long‡, Zhi Guan*, Yan-Hong He*. Selective electrochemical oxidation of tetrahydroquinolines to 3,4-dihydroquinolones. Green Chem., 2022, 24(11), 4581-4587.
[14] Ling-Po Li, Xin Cai, Yang Xiang, Yong Zhang, Jian Song, Da-Cheng Yang, Zhi Guan* Yan-Hong He*. The α-chymotrypsin-catalyzed Povarov reaction: one-pot synthesis of tetrahydroquinoline derivatives. Green Chem., 2015, 17(5), 3148-3156.
[15] Chang-Heng Wang, Zhi Guan, and Yan-Hong He*. Biocatalytic domino reaction: synthesis of 2H-1-benzopyran-2-one derivatives using alkaline protease from Bacillus licheniformis. Green Chem., 2011, 13(8), 2048-2054.
[16] Hai-Hong Li, Yan-Hong He, Yi Yuan and Zhi Guan*. Nuclease p1: A new biocatalyst for direct asymmetric aldol reaction under solvent-freeconditions. Green Chem., 2011, 13(1), 185-189.
[17] Xiao-Wen Wang, Yang Deng, Rui-Xue Li, Jin-Feng Lv, Ming-Qiu-Hao Fu, Zhi Guan*, Ya-Nan Zhao*, Yan-Hong He*. Electrochemical direct formyloxylation of benzylic C(sp3)–H with DMF. ACS Sustainable Chem. Eng., 2023, 11(5), 1624-1630.
[18] Chao-Jiu Long,‡ Hong-Ping Pu,‡ Yan-Hong He*, Zhi Guan*. Direct enantioselective α-alkylation of secondary acyclic amines with ketones by combining photocatalysis and lipase catalytic promiscuity. Org. Chem. Front., 2023, 10(20), 5108-5116.
[19]. Chun-Lin Dong, Zhi Guan*, Yan-Hong He*. Direct acylcyanation of aryl alkenes by dual photoredox and copper catalysis. Org. Chem. Front., 2023, 10(16), 4016-4022.
[20] Chao-Jiu Long, Hong-Ping Pu, Ya-Nan Zhao, Yan-Hong He*, Zhi Guan*. Cooperative photocatalysis and L-/D-proline catalysis enables enantioselective oxidative cross-dehydrogenative coupling of acyclic benzylic secondary amines with ketones. Org. Chem. Front., 2023, 10(9), 2177–2185.
