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向云
发布时间: 2015-12-15 10:02:23   作者:本站编辑   来源: 本站原创   浏览次数:


向云

教授,博士生导师,教育部新世纪优秀人才

个人简介(300-500字)

分别于19997月和20037月毕业于四川大学化学学院,获学士和硕士学位,200812月毕业于美国亚利桑那州立大学(Arizona State University)化学与生物化学系,获博士学位。20091月被引进到西南大学化学化工学院工作,20116月晋升教授。 目前主持或完成国家自然科学基金3项,省部级自然科学基金5项,2012年获教育部新世纪优秀人才计划资助。开展研究工作以来,以通讯作者在Anal. Chem.18篇)、Chem. Commun. 17篇)、Nanoscale5篇)、 ACS Appl. Mater. Interfaces4篇)和Biosens. Bioelectron. 24篇)等杂志发表论文110余篇。

联系方式

Emailyunatswu@swu.edu.cn

For English version, please visit: http://sites.google.com/site/yunxiangswu/

研究方向

电分析化学(Electroanalysis)、生物成像(Bio-imaging)、DNA纳米生物技术(DNA Nanobiotechnology

代表性论文、专著和专利(不超过20项)

1.     Jianmei Yang, Xiaolong Li, Bingying Jiang,* Ruo Yuan, Yun Xiang,* In Situ-Generated Multivalent Aptamer Network for Efficient Capture and Sensitive Electrochemical Detection of Circulating Tumor Cells in Whole Blood, Analytical Chemistry, 2020, 92, 7893−7899.

2.     Daxiu Li, Tingting Zhang, Fang Yang, Ruo Yuan,* Yun Xiang,* Efficient and Exponential Rolling Circle Amplification Molecular Network Leads to Ultrasensitive and Label-Free Detection of MicroRNA, Analytical Chemistry, 2020, 92, 2074−2079.

3.     Baoting Dou, Jin Li, Bingying Jiang,* Ruo Yuan, Yun Xiang,* DNA-templated in situ synthesis of highly dispersed AuNPs on nitrogen-doped graphene for real-time electrochemical monitoring of nitric oxide released from live cancer cells, Analytical Chemistry, 2019, 91, 2273−2278.

4.     Wenjiao Zhou, Daxiu Li, Ruo Yuan, Yun Xiang,* Programmable DNA ring/hairpin-constrained structure enables ligation-free rolling circle amplification for imaging mRNAs in single cells, Analytical Chemistry, 2019, 91, 3628−3635.

5.     Baoting Dou, Lin Xu, Bingying Jiang,* Ruo Yuan, Yun Xiang,* Aptamer-functionalized and gold nanoparticle array-decorated magnetic graphene nanosheets enable multiplexed and sensitive electrochemical detection of rare circulating tumor cells in whole blood, Analytical Chemistry, 2019, 91, 10792−10799.

6.     Yao Qin, Daxiu Li, Ruo Yuan, Yun Xiang,* Netlike hybridization chain reaction assembly of DNA nanostructures enables exceptional signal amplification for sensing trace cytokines, Nanoscale, 2019, 11, 16362−16367.

7.     Xia Li, Jianmei Yang, Ruo Yuan, Yun Xiang,* Programming cascaded recycling amplifications for highly sensitive and label-free electrochemical sensing of transcription factors in tumor cells, Biosensors and Bioelectronics, 2019, 142, 111574.

8.     Jianmei Yang, Xiaotong Huang, Chunfang Gan,* Ruo Yuan, Yun Xiang,* Highly specific and sensitive point-of-care detection of rare circulating tumor cells in whole blood via a dual recognition strategy, Biosensors and Bioelectronics, 2019, 143, 111604.

9.     Baoting Dou, Jianmei Yang, Ruo Yuan, Yun Xiang,* Trimetallic hybrid nanoflower-decorated MoS2 nanosheet sensor for direct in situ monitoring of H2O2 secreted from live cancer cells, Analytical Chemistry, 2018, 90, 5945−5950.

10.    Daxiu Li, Yulan Wu, Chunfang Gan, Ruo Yuan, Yun Xiang,* Bio-cleavable nanoprobes for target-triggered catalytic hairpin assembly amplification detection of microRNAs in live cancer cells, Nanoscale, 2018, 10, 17623.

11.    Xia Li, Jianmei Yang, Jiaqing Xie, Bingying Jiang*, Ruo Yuan, Yun Xiang,* Cascaded signal amplification via target-triggered formation of aptazyme for sensitive electrochemical detection of ATP, Biosensors & Bioelectronics, 2018, 102, 296–300.

12.    Ying Peng, Daxiu Li, Ruo Yuan, Yun Xiang,* A catalytic and dual recycling amplication ATP sensor based on target driven allosteric structure switching of aptamer beacons, Biosensors & Bioelectronics, 2018, 105, 1–5.

13.    Daxiu Li, Wenjiao Zhou, Ruo Yuan, Yun Xiang,* A DNA-fueled and catalytic molecule machine lights up trace under-expressed microRNAs in living cells, Analytical Chemistry, 2017, 89, 9934−9940.

14.    Jianmei Yang, Baoting Dou, Ruo Yuan, Yun Xiang,* An aptamer/protein proximity binding-triggered molecular machine for amplified electrochemical sensing of thrombin, Analytical Chemistry, 2017, 89, 5138−5143.

15.    Xin Li, Jiaqing Xie, Bingying Jiang*, Ruo Yuan, Yun Xiang,* Metallo-toehold-activated catalytic hairpin assembly formation of three-way DNAzyme junctions for amplified fluorescent detection of Hg2+, ACS Applied Materials & Interfaces, 2017, 9, 5733−5738.

16.    Jing Li, Daxiu Li, Ruo Yuan, Yun Xiang,* Nanosheet-mediated signal amplification in living cells enables sensitive detection of down-regulated intracellular microRNA, ACS Applied Materials & Interfaces, 2017, 9, 5717−5724.

17.    Jianmei Yang, Baoting Dou, Ruo Yuan, Yun Xiang,* Proximity binding and metal ion-dependent DNAzyme cyclic amplification-integrated aptasensor for label-Free and sensitive electrochemical detection of thrombin, Analytical Chemistry, 2016, 88, 8218−8223.

18.     Ying Peng, Xin Li, Ruo, Yun Xiang,* Steric hindrance inhibition of strand displacement for homogeneous and signal-on fluorescence detection of human serum antibodies, Chemical Communications, 2016, 52, 1258612589.

19.    Cuiyun Yang, Baoting Dou, Jianmei Yang, Ruo Yuan, Yun Xiang,* Cross-triggered and cascaded recycling amplification for ultrasensitive electrochemical sensing of the mutant human p53 gene, Chemical Communications, 2016, 52, 87078710.

20.    Yun Xiang, Mingyi Xie, Ralph Bash, Julian J. L. Chen, Joseph Wang,* Ultrasensitive label-free aptamer-based electronic detection, Angewandte Chemie-International Edition, 2007, 46, 9054–9056.