向云
教授，博士生导师，教育部新世纪优秀人才
个人简介（300-500字）
分别于1999年7月和2003年7月毕业于四川大学化学学院，获学士和硕士学位，2008年12月毕业于美国亚利桑那州立大学（Arizona State University）化学与生物化学系，获博士学位（导师 Joseph Wang教授）。2009年1月被引进到西南大学化学化工学院工作，2011年6月晋升教授。 目前主持或完成国家自然科学基金5项，省部级自然科学基金5项，2012年获教育部新世纪优秀人才计划资助。独立开展研究工作以来，以通讯作者在J. Am. Chem. Soc.（1）; Chem. Sci.（2）; Anal. Chem.（24）; Chem. Eng. J.（2）; Chem. Commun.（14）; ACS Appl. Mater. Interfaces（5）和Biosens. Bioelectron.（25）等杂志发表论文200余篇。
联系方式
Email：yunatswu@swu.edu.cn
研究方向
电分析化学（Electroanalysis）、生物成像（Bio-imaging）、DNA纳米生物技术（DNA Nanobiotechnology）
代表性论文、专著和专利（不超过20项）
1.Xinmei Song, Xin Bi, Shunmei Li, Ruo Yuan,* Yun Xiang,* In Vivo Spatiotemporal Protection and Recognition of Circulating Tumor DNA for Early Cancer Diagnosis and Monitoring, Journal of the American Chemical Society, 2026, https://doi.org/10.1021/jacs.6c00261
2.Jianmei Yang,* Qianhong Chen, Ruo Yuan, and Yun Xiang,* Highly Catalytic FeS2@CoS2 Core/Shell Nanocubes for Ultrasensitive Electrochemical Assay of Microphthalmia-Associated Transcription Factor via Nucleic Acid Signal Amplification Cascades, Analytical Chemistry, 2025, 97, 27716−27723.
3.Fang Yang, Shunmei Li, Xin Bi, Ruo Yuan, Yun Xiang,* DNA-Assembled Size-Permeable Microcapsule Bioreactor Enables Direct and Rapid Sensing of Trace Circulating MicroRNA Biomarker in Undiluted Cancer Patient Serum, Analytical Chemistry, 2025, 97, 2845−2852.
4.Shunmei Li, Fang Yang, Xin Bi, Ruo Yuan, Yun Xiang,* Protein-bridged size-permeable DNAzyme@PEG hollow nanosphere reactor facilitates direct and rapid monitoring of trace circulating microRNAs in undiluted cancer patient serums, Chemical Engineering Journal 2024, 500, 156649.
5.Daxiu Li,* Yinghan Liu, Yuhao Li, Yun Xiang,* Ruo Yuan, Simultaneous and Sensitive Sensing of Intracellular MicroRNA and mRNA for the Detection of the PI3K/AKT Signaling Pathway in Live Cells, Analytical Chemistry, 2024, 96, 3329−3334.
6.Shunmei Li, Xin Bi, Huaifeng Yan, Bingying Jiang,* Ruo Yuan, Yun Xiang,* Engineering metal ion-coordinated DNA nanospheres for precise detection of specific chemoresistance-dependent signaling pathway and reversion in live cancer cells, Chemical Engineering Journal 2024, 523, 168886.
7.Fang Yang, Shunmei Li, Xin Bi, Ruo Yuan, and Yun Xiang,* Multicolor-Encoded DNA Framework Enables Specific and Amplified In Situ Detection of the Mitochondrial Apoptotic Signaling Pathway, Analytical Chemistry, 2023, 95, 12514−12520.
8.Fang Yang, Shunmei Li, Xia Li, Ruo Yuan, and Yun Xiang,* Robust DNA Cross-Linked Polymeric Lighting-Up Nanogel Facilitates Sensitive Live Cell MicroRNA Imaging, Analytical Chemistry, 2022, 94, 16079−16085.
9.Wenjiao Zhou, Fang Yang, Shunmei Li, Ruo Yuan, Yun Xiang,* A stimulus-responsive hexahedron DNA framework facilitates targeted and direct delivery of native anticancer proteins into cancer cells, Chemical Science, 2022, 13, 11132–11139.
10.Xia Li, Fang Yang, Shunmei Li, Ruo Yuan, Yun Xiang,* Size-discriminative DNA nanocage framework enables sensitive and high-Fidelity imaging of mature microRNA in living cells, Analytical Chemistry, 2022, 94, 9927−9933.
11.Fang Yang, Xia Li, Ruo Yuan, Yun Xiang,* High fidelity and simultaneous sensing of endogenous mutant and wild p53 proteins for precise cancer diagnosis and drug Screening, Analytical Chemistry, 2021, 93, 8084−8090.
12.Xia Li, Fang Yang, Wenjiao Zhou, Ruo Yuan, Yun Xiang,* Targeted and direct intracellular delivery of native DNAzymes enables highly specific gene silencing, Chemical Science, 2020, 11, 8966-8972.
13.Jianmei Yang, Xiaolong Li, Bingying Jiang,* Ruo Yuan, Yun Xiang,* In Situ-Generated Multivalent Aptamer Network for Efficient Capture and Sensitive Electrochemical Detection of Circulating Tumor Cells in Whole Blood, Analytical Chemistry, 2020, 92, 7893−7899.
14.Daxiu Li, Tingting Zhang, Fang Yang, Ruo Yuan,* Yun Xiang,* Efficient and Exponential Rolling Circle Amplification Molecular Network Leads to Ultrasensitive and Label-Free Detection of MicroRNA, Analytical Chemistry, 2020, 92, 2074−2079.
15.Baoting Dou, Jin Li, Bingying Jiang,* Ruo Yuan, Yun Xiang,* DNA-templated in situ synthesis of highly dispersed AuNPs on nitrogen-doped graphene for real-time electrochemical monitoring of nitric oxide released from live cancer cells, Analytical Chemistry, 2019, 91, 2273−2278.
16.Baoting Dou, Lin Xu, Bingying Jiang,* Ruo Yuan, Yun Xiang,* Aptamer-functionalized and gold nanoparticle array-decorated magnetic graphene nanosheets enable multiplexed and sensitive electrochemical detection of rare circulating tumor cells in whole blood, Analytical Chemistry, 2019, 91, 10792−10799.
17.Baoting Dou, Jianmei Yang, Ruo Yuan, Yun Xiang,* Trimetallic hybrid nanoflower-decorated MoS2 nanosheet sensor for direct in situ monitoring of H2O2 secreted from live cancer cells, Analytical Chemistry, 2018, 90, 5945−5950.
18.Daxiu Li, Wenjiao Zhou, Ruo Yuan, Yun Xiang,* A DNA-fueled and catalytic molecule machine lights up trace under-expressed microRNAs in living cells, Analytical Chemistry, 2017, 89, 9934−9940.
19.Jianmei Yang, Baoting Dou, Ruo Yuan, Yun Xiang,* Proximity binding and metal ion-dependent DNAzyme cyclic amplification-integrated aptasensor for label-Free and sensitive electrochemical detection of thrombin, Analytical Chemistry, 2016, 88, 8218−8223.
20.Yun Xiang, Mingyi Xie, Ralph Bash, Julian J. L. Chen, Joseph Wang,* Ultrasensitive label-free aptamer-based electronic detection, Angewandte Chemie-International Edition, 2007, 46, 9054–9056.
